Search results for: Massimo Cugno
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Cleavage of high molecular weight kininogen in ascites and plasma of patients with cirrhosis
Thrombosis Research > 1995 > 78 > 4 > 277-282
The vasoactive peptide bradykinin may be involved in the pathogenesis of vasodilation, which has been considered the initiating event of ascites formation in cirrhotic patients. Since bradykinin is generated through the cleavage of high molecular weight kininogen (HK) by kallikrein, we looked for the cleavage of HK by an immunoblotting technique in plasma and ascitic fluid of 28 patients with cirrhosis...
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