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Renal‐clearable nanoparticles have made it possible to overcome the toxicity by nonspecific accumulation in healthy tissues/organs due to their highly efficient clearance characteristics. However, their tumor uptake is relatively low due to the short blood circulation time and rapid body elimination. Here, this problem is addressed by developing renal‐clearable nanoparticles by controlled coating...
In article number 1704634, Mei Tian, Jie Tian, Min Zhou, and co‐workers present clearable nanoparticles for image‐guided cancer therapy. CuS nanodots@mesoporous silica nanoparticles allow for positron emission/photoacoustic bimodal imaging and effective chemo‐photothermal therapy. Irradiating the particles with a near‐infrared laser forms ultrasmall nanoparticles and fragments that exhibit high body...
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