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We compared osteoclast (OC) formation in bone marrow–derived macrophages (BMM) from C57BL/6 (B/6) and BALB/c (B/c) mice. After stimulation of receptor activator of nuclear factor-κB ligand (RANKL), enhanced OC formation and higher level of macrophage inflammatory protein-1α (MIP-1α) were observed in the BMM from B/c mice. In this study, we determined whether MIP-1α is responsible for stimulated OC...
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