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The aim of the present study was to determine drug-α 1D adrenergic receptor (AR) affinity by frontal analysis of cell-membrane chromatography (CMC). The cell-membrane stationary phase (CMSP) was prepared by immobilizing rat aorta cell membranes on porous silica, and the resulting CMSP was used to determine drug binding affinity to α 1D -AR by frontal analysis. The CMSP of rat aorta...
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