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Triple‐negative breast cancer (TNBC) is characterized by strong invasiveness, high relapse rates, and poor overall survival. It occurs in approximately 15–20 % of all breast cancer cases. Natural compounds are a promising option for managing breast cancer. ent‐8(14),15‐Pimaradiene‐2β,19‐diol (JXE‐23), is a pimaradiene isolated from the fern Aleuritopteris albofusca. However, the effects and molecular...
Ethoxysanguinarine (ESG) is a benzophenanthridine alkaloid extracted from plants of Papaveraceae family, such as Macleaya cordata (Willd) R. Br. The anti‐cancer activity of ESG has been rarely reported. In this study, we investigated the anti‐breast cancer effect of ESG and its underlying mechanism. MTT assay and flow cytometry analysis showed that ESG inhibited the viability and induced apoptosis...
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