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2-Amino-6-[ 18 F]fluoro-9-(4-hydroxy-3-hydroxy-methylbutyl) purine (6-[ 18 F]FPCV) was prepared via a one-step nucleophilic substitution and evaluated as a novel probe for imaging the expression of herpes simplex virus type 1 thymidine kinase (HSV1-tk) reporter gene.Log P of 6-[ 18 F]FPCV was calculated in octanol/phosphate-buffered saline (PBS). Stability studies were performed...
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