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Human immunodeficiency virus type-1 (HIV-1)-specific dendritic cell (DC) vaccines have been applied to clinical trials that show only induction of some degree of immune responses, warranting the search of other more efficient vaccine strategies. Since HIV-1-specific CD8+ cytotoxic T lymphocytes (CTLs) have been found to recognize some HIV-1 structural protein Gag conserved and cross-strain epitopes,...
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