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Copper‐induced toxicity is important in the pathogenic process of Wilson's disease (WD). Using Long–Evans Cinnamon (LEC) rats, an animal model of WD, the study was undertaken to identify proteins involved in the process of WD and to investigate their functional roles in copper‐induced hepatotoxicity. In early stages, expression levels of mitochondrial matrix proteins including agmatinase, isovaleryl...
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