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Nicotinoylamino acid compounds 4, 5, 9a, 9b, 9c, 10a and 10b were synthesized with nicotinoyl chloride or nicotinoyl azide as acetylating agents of amino acid esters or amino acids. The compounds were tested for their radiosensitizing activity in Leukemia cell line(L 1210 ) and compared with nicotinamide; among them, compounds 9a and 9c showed significant radiosensitizing effects, the sensitizer...
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