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Background ALK-rearranged non-small cell lung cancer (NSCLC) represents a molecular subgroup with high sensitivity to ALK inhibitors. Crizotinib, a US Food and Drug Administration (FDA)-approved tyrosine kinase inhibitor for treating ALK-rearranged NSCLC, has shown remarkable response in ALK-positive NSCLC. However, heterogeneity of clinical responses exists among different ALK fusion partners. Several...
In this paper, a novel biomimetic walking grasp-type underwater microrobot, which looked like a crab with eight legs, was presented at first. The intermediate four legs are made of one piece of ICPF (Ionic Conducting Polymer Film) and two pieces of plastic flake used for grasping and releasing objects; the other four legs which are used for walking are made up of two pieces of ICPFs. The structure...
This paper presents the research toward a small autonomous biomimetic microrobot that can swim in a 3D environment. The overall size of the microrobot is 99 mm in length, 36 mm in width, and 22 mm in thickness. The microrobot is propelled by ICPF (ionic conducting polymer film) actuators which act as caudal fin and pectoral fins respectively. Infrared sensors are equipped on the microrobot for wireless...
A centimeter-scale robotic fish is proposed and realized in this paper. The robotic fish mimics a type of small crucian. Its swimming pattern of cruise-straight, cruise-in-turning, burst and coast are realized respectively. The remote control function is realized at the base of an infrared sensor. An IPMC actuator and two pieces of PVC film construct a caudal fin to mimic the swing of the small crucian...
This paper presents the research toward centimetre-scale autonomous robotic fish mimicking a kind of goldfish. The robotic fish is propelled by an iconic polymer-metal composite (IPMC) actuator and equipped with a microcontroller and an infrared sensor for wireless control, autonomous navigation and obstacle avoidance. To improve turning ability of the robotic fish, we set the length of caudal fin...
-In this paper, a new type of underwater microrobot is proposed. The microrobot is driven by two pieces of ICPF (Ionic Conducting Polymer Film) actuators. An infrared sensor is equipped in front of the microrobot for motion guidance and obstacle avoidance. The dimension of the microrobot is 53 mm*8 mm*20 mm in size. The dried weight of the microrobot is 3g. The microrobot can float in water, swim...
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