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Optogenetics is a fast growing neuromodulation method, which can remotely manipulate the specific activities of genetically-targeted neural cells and associated biological behaviors with millisecond temporal precision through light illumination. Application of optogenetics in neuroscience studies has created an increased need for the development of light sources and the instruments for light delivery...
This paper reports a method of making optical probes for optogenetics-based deep brain optical stimulation using SU-8, which effectively increases light coupling efficiency, has excellent mechanical stiffness, and reduces fabrication complexity. By mounting microscale LEDs (μLEDs) at the tip of a SU-8 probe and directly inserting the light source into deep brain regions, attenuation caused by light...
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