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A novel glucose sensing strategy by using bi-enzyme coated monodispered silica nanoparticles (SiO 2 ) was proposed. The monodispered SiO 2 was synthesized according to our previously reported seed-growth methods. Glucose oxidase (GOD) and horseradish peroxidase (HRP) were simultaneously covalent immobilized on the surface of SiO 2 nanoparticles through the cross-linker of glutaraldehyde...
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