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MicroRNA-126 (miR-126) expression has been shown to be associated with angiogenesis. The aim of the current study is to evaluate the functional roles of miR-126 in dysregulation of VEGF expression and cancer progression in thyroid carcinomas. The expression of VEGF-A and miR-126 were measured in 101 thyroid carcinomas tissues (including 51 conventional papillary thyroid carcinoma, 37 follicular variant...
The objectives of this study are to investigate the expression of miR-126 and evaluate its effect on proliferation in undifferentiated thyroid carcinoma.miR-126 expression of undifferentiated thyroid carcinoma cell lines 8505C (BRAFV600E/V600E), BHT-101 (BRAFV600E/WT) and MB-1 (BRAFWT/WT) were quantified with q-PCR. These cell lines were transiently transfected with exogenous miR-126 (mimic). Following...
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