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BACKGROUND:There is a crucial need for better therapeutic approaches for the treatment of Ewing sarcoma (EWS). Tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL) induces apoptosis in EWS cells in vitro. However, in vivo, acquired resistance to TRAIL is a major limiting factor. Platelet‐derived growth factor receptor‐β (PDGFR‐β) is highly expressed on EWS cells. Thus, the authors evaluated...
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