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Overexpression of the epidermal growth factor receptor (EGFR) has been implicated in the development of non‐small‐cell lung cancer (NSCLC). Thus, EGFR is an effective drug target for the treatment of NSCLC, and developing fourth‐generation EGFR inhibitors to overcome the resistance mediated by T790M/C797S mutations are currently under investigation. In this study, based on the binding model between...
The blockade of the overexpression of pro‐inflammatory cytokines by anti‐inflammatory natural products has been proven therapeutically beneficial in the treatment of acute lung injury (ALI). Given the fact that cinnamic acid has been proven to have significant anti‐inflammatory activity, we selected it as a promising lead compound to develop more effective analogs in treating ALI. Learning from the...
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