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Biosynthesis
A cell‐free membrane protein synthesis system (CFMPS) with natural or artificial lipid biomembranes is constructed, to effectively synthesize full‐length transmembrane proteins by improving the membrane protein solubility and assisting the active structure formation, as described by Yuan Lu and co‐workers in article number 2300575. The CFMPS can be further extended to expand the toolbox...
The angiotensin‐converting enzyme 2 (ACE2), as a functional receptor for severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is essential for assessing potential hosts and treatments. However, many studies are based on its truncated version but not full‐length structure. Indeed, a single transmembrane (TM) helix presents in the full‐length ACE2, influencing its interaction with SARS‐CoV‐2...
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