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At present the role of autophagy in cell death and cell survival remains controversial, partly owning to the contradictory results from the immortalized mouse embryonic fibroblasts (MEFs) with knockout of different autophagy-related genes (Atg). Here we aimed to reexamine the role of autophagy in cell death under starvation and other stress conditions. First, different clones of Atg5 knockout MEFs...
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