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Advances in nano‐/microfabrication allow the fabrication of biomimetic substrates for various biomedical applications. In particular, it would be beneficial to control the distribution of cells and relevant biomolecules on an extracellular matrix (ECM)‐like substrate with arbitrary micropatterns. In this regard, the possibilities of patterning biomolecules and cells on nanofibrous matrices are explored...
With the assistance of an ink‐jet printer, solvent (the “ink”) can be controllably and reproducibly printed onto electrospun nanofiber meshes (the “paper”) to generate various micropatterns and subsequently guide distinct cellular organization and phenotype expression. In combination with the nanofiber‐assisted layer‐by‐layer cell assembly, the patterned electrospun meshes will define an instructive...
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