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The aim of the present study was to evaluate the effect of Tob1 on the radiosensitivity of breast cancer cells. The results showed that overexpression of Tob1 reduced the clonogenic growth of 231 cells and induced the rate of apoptosis. Tob1 caused an accumulation of cells in the G0/G1 phase and decreased the percentage of cells in S phase. We also found that overexpression of Tob1 significantly reduced...
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