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The design, construction, assembly, and testing of a compact and portable fiber optic-based dynamic light scattering instrument are reported. The noninvasive instrument integrates latest solid state and fiber optic technologies to study the ocular fluids and tissues from the cornea to the retina in the eyes of live animals in field applications.
Investigating the effect of retinal oxygenation abnormalities in the development of common eye diseases requires accurate assessment of oxygen tension in retinal vasculatures. Estimation of oxygen tension in retinal capillaries using phosphorescence lifetime imaging is addressed in this paper. Separation from tissue and oxygen tension estimation is a more challenging task for capillaries when compared...
The role of inadequate retinal oxygenation in the development of retinal diseases is an important problem for investigation. In our study, quantitative measurement of oxygen tension in retinal vasculatures is made with the noninvasive technique of phosphorescence lifetime imaging. A frequency domain approach is used to estimate the fluorescence or phosphorescence lifetime by regression analysis. Measurements...
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