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BACKGROUND
Human neutrophil antigen‐3 (HNA‐3) alloantibodies can cause fatal transfusion‐related acute lung injury (TRALI). Most frequencies of SLC44A2 alleles encoding the HNA‐3a/b antigens have been established in Han individuals by polymerase chain reaction with sequence‐specific priming (PCR‐SSP). We sequenced SLC44A2 gene fragments and determined allele frequencies in three ethnicities of China...
BACKGROUND
Human neutrophil antigen‐3a (HNA‐3a) alloantibodies can cause severe transfusion‐related acute lung injury. The frequencies of the single‐nucleotide polymorphisms (SNPs) indicative of the two clinically relevant HNA‐3a/b antigens are known in many populations. In this study, we determined the full‐length nucleotide sequence of common SLC44A2 alleles encoding the choline transporter–like...
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