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Objective
We determined the bacterial community structure of the buccal mucosa in patients with oral lichen planus (OLP) and evaluated the potential association of Fusobacterium nucleatum with OLP.
Subjects and Methods
We collected buccal mucosal swab samples of patients with OLP (n = 20) and healthy controls (n = 10) and performed 16S rRNA gene sequencing and real‐time PCR to determine potentially...
J Oral Pathol Med (2011) 40: 525–532
Background: Oral lichen planus (OLP) is a T‐cell‐mediated chronic autoimmune disease whose precise etiology is unknown. The recently identified costimulatory programmed death‐1 (PD‐1) molecule and its ligands, PD‐L1 and PD‐L2, have been identified as CD28‐B7 family molecules and constitute a regulatory pathway of potential therapeutic use in immune‐mediated diseases...
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