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A steep electric pulsed field with low intensity (150–250V/cm) and relative long time (10min) was applied to adherent liver cancer cell line SMMC-7721 and the liver cell line HL-7702. Results showed that the electric field with intensity of 200 and 250V/cm could trigger cell apoptosis, whereas the SMMC-7721 cell was more sensitive to the electric stimulation than the HL-7702 cell. Laser Scanning Confocal...
The wild-type p53 is investigated whether it has an effect on apoptosis and cell cycle distribution of K562 cells after EMP irradiation. The K562 cells transfected with wild-type p53 were irradiated by EMP and then cultured for 18h. Apoptosis and cell cycle were detected by FCM. Apoptosis and G1 arrest were induced by p53 transfection. No effect of EMP was detected on cell cycle and apoptosis of K562...
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