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To determine the response to radionuclide targeted therapy with I-131-metaiodobenzylguanidine ( 131 I-MIBG) as induction therapy in high-risk neuroblastoma patients.The protocol dictated at least two cycles of 131 I-MIBG with a fixed dose of 7.4 and 3.7 GBq, respectively, followed by surgery, if feasible, or followed by neoadjuvant chemotherapy and surgery. This was followed by consolidation...
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