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Expression of miR‐34c is significantly reduced in human endometrial cancer cells and miR‐34c regulates multiple genes associated with cancer cell proliferation, apoptosis and invasiveness. Thus, miR‐34c can theoretically become a target that enhances chemotherapy. Upregulation of miR‐34c to enhance the chemotherapeutic effect of cisplatin (DDP) has not been studied in human endometrial cancer cells...
Glioma is the most common primary intracranial malignant tumor. Despite advances in surgical techniques and adjuvant radio- and chemotherapies, the prognosis for patients with glioma remains poor. We have explored the effects of using genetically modified mesenchymal stem cells (MSCs) to treat malignant glioma in rats. Mesenchymal stem cells isolated from Sprague–Dawley rats can directly suppress...
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