Search results for: Sebastian Müller

Items from 1 to 20 out of 139 results

article

A 19‐color single‐tube full spectrum flow cytometry assay for the detection of measurable residual disease in acute myeloid leukemia

Hendrik Fokken, Julian Waclawski, Nadine Kattre, Arnold Kloos, more

Multiparameter flow cytometry (MFC) has emerged as a standard method for quantifying measurable residual disease (MRD) in acute myeloid leukemia. However, the limited number of available channels on conventional flow cytometers requires the division of a diagnostic sample into several tubes, restricting the number of cells and the complexity of immunophenotypes that can be analyzed. Full spectrum...

article

Grammar‐based fuzzing of data integration parsers in computational materials science

Sebastian Müller, Jan Arne Sparka, Martin Kuban, Claudia Draxl, more

Software: Practice and Experience > 54 > 2 > 208 - 224

Context Computational materials science (CMS) focuses on in silico experiments to compute the properties of known and novel materials, where many software packages are used in the community. The NOMAD Laboratory (Draxl C, Scheffler) offers to store the input and output files in its FAIR data repository. Since the file formats of these software packages are non‐standardized, parsers are used to provide...

article

How to Find Aquifer Statistics Utilizing Pumping Tests? Two Field Studies Using welltestpy

Sebastian Müller, Carsten Leven, Peter Dietrich, Sabine Attinger, more

Groundwater > 60 > 1 > 137 - 144

We present a workflow to estimate geostatistical aquifer parameters from pumping test data using the Python package welltestpy. The procedure of pumping test analysis is exemplified for two data sets from the Horkheimer Insel site and from the Lauswiesen site, Germany. The analysis is based on a semi‐analytical drawdown solution from the upscaling approach Radial Coarse Graining, which enables to...

article

Do consumers care about work health issues? A qualitative study on voluntary occupational health activities and consumer social responsibility

Sebastian Müller, Eva Kuhn, Alena Buyx, Ludger Heidbrink

Business and Society Review > 126 > 2 > 169 - 191

As occupational health management (OHM) and work health promotion (WHP) become increasingly prominent in companies worldwide, little is known about consumers' attitudes towards work health‐related issues. Do consumers consider the health of employees in German companies to be important? Do German companies consider consumers to be relevant stakeholders in voluntary occupational health (OH) and well‐being...

article

ogs5py: A Python‐API for the OpenGeoSys 5 Scientific Modeling Package

Sebastian Müller, Alraune Zech, Falk Heße

Groundwater > 59 > 1 > 117 - 122

High‐performance numerical codes are an indispensable tool for hydrogeologists when modeling subsurface flow and transport systems. But as they are written in compiled languages, like C/C++ or Fortran, established software packages are rarely user‐friendly, limiting a wider adoption of such tools. OpenGeoSys (OGS), an open‐source, finite‐element solver for thermo‐hydro‐mechanical–chemical processes...

article

Cover Feature: Salinomycin Derivatives Kill Breast Cancer Stem Cells by Lysosomal Iron Targeting (Chem. Eur. J. 33/2020)

Antoine Versini, Ludovic Colombeau, Antje Hienzsch, Christine Gaillet, more

Chemistry – A European Journal > 26 > 33 > 7334 - 7334

Fluorescence microscopy images of lysosomal staining with lysotracker in HMLER CD44^high/CD24^low cells treated with the C20‐cyclopropylamine Salinomycin derivative and a model of its crystal structure. Salinomycin derivatives and DMT1 inhibitors (DOI: 10.1002/chem.202000335 and DOI: 10.1002/chem.202000159) selectively target cancer stem cells via lysosomal iron accumulation. Reactive oxygen species...

article

Salinomycin Derivatives Kill Breast Cancer Stem Cells by Lysosomal Iron Targeting

Antoine Versini, Ludovic Colombeau, Antje Hienzsch, Christine Gaillet, more

Chemistry – A European Journal > 26 > 33 > 7416 - 7424

Salinomycin (1) exhibits a large spectrum of biological activities including the capacity to selectively eradicate cancer stem cells (CSC), making it and its derivatives promising candidates for the development of drug leads against CSC. It has been previously shown that salinomycin and its C20‐propargylamine derivative (Ironomycin (2)) accumulate in lysosomes and sequester iron in this organelle...

article

DMT1 Inhibitors Kill Cancer Stem Cells by Blocking Lysosomal Iron Translocation

Andreea L. Turcu, Antoine Versini, Nadjib Khene, Christine Gaillet, more

Chemistry – A European Journal > 26 > 33 > 7369 - 7373

Cancer stem cells (CSC) constitute a cell subpopulation in solid tumors that is responsible for resistance to conventional chemotherapy, metastasis and cancer relapse. The natural product Salinomycin can selectively target this cell niche by directly interacting with lysosomal iron, taking advantage of upregulated iron homeostasis in CSC. Here, inhibitors of the divalent metal transporter 1 (DMT1)...

article

Image‐Based Morphological Profiling Identifies a Lysosomotropic, Iron‐Sequestering Autophagy Inhibitor

Luca Laraia, Guillaume Garivet, Daniel J. Foley, Nadine Kaiser, more

Angewandte Chemie International Edition > 59 > 14 > 5721 - 5729

Chemical proteomics is widely applied in small‐molecule target identification. However, in general it does not identify non‐protein small‐molecule targets, and thus, alternative methods for target identification are in high demand. We report the discovery of the autophagy inhibitor autoquin and the identification of its molecular mode of action using image‐based morphological profiling in the cell...

article

Image‐Based Morphological Profiling Identifies a Lysosomotropic, Iron‐Sequestering Autophagy Inhibitor

Luca Laraia, Guillaume Garivet, Daniel J. Foley, Nadine Kaiser, more

Angewandte Chemie > 132 > 14 > 5770 - 5778

article

The new LassoLoop360° technique for biomechanically superior tissue grip

Sebastian Müller, Rebekka Flury, Simon Zimmermann, Michael Wild, more

Knee Surgery, Sports Traumatology, Arthroscopy > 2019 > 27 > 12 > 3962-3969

Purpose Suprapectoral tenodesis is a frequently used technique for treating pathologies of the long head of the biceps brachii (LHBB) tendon. However, so far, no Gold Standard treatment exist. Hence, the arthroscopic LassoLoop360 (LL360) technique is introduced aiming to provide secure fixation and improved biomechanical properties. It was hypothesized, that the LL360 technique would show superior...

article

Einstein Relation for Random Walk in a One-Dimensional Percolation Model

Nina Gantert, Matthias Meiners, Sebastian Müller

Journal of Statistical Physics > 2019 > 176 > 4 > 737-772

We consider random walks on the infinite cluster of a conditional bond percolation model on the infinite ladder graph. In a companion paper, we have shown that if the random walk is pulled to the right by a positive bias $$\uplambda > 0$$ λ > 0 , then its asymptotic linear speed $$\overline{\mathrm {v}}$$ v ¯ is continuous in the variable $$\uplambda > 0$$ λ > 0 ...

article

Dielectric–Semiconductor Interface Limits Charge Carrier Motion at Elevated Temperatures and Large Carrier Densities in a High‐Mobility Organic Semiconductor

Ilja Vladimirov, Sebastian Müller, Roelf‐Peter Baumann, Thomas Geßner, more

Advanced Functional Materials > 29 > 12 > n/a - n/a

The fundamental nature of charge transport in highly ordered organic semiconductors is under constant debate. At cryogenic temperatures, effects within the semiconductor such as traps or the interaction of charge carriers with the insulating substrate (dipolar disorder or Fröhlich polarons) are known to limit carrier motion. In comparison, at elevated temperatures, where charge carrier mobility often...

article

Structure-based design and profiling of novel 17β-HSD14 inhibitors

Florian Braun, Nicole Bertoletti, Gabriele Möller, Jerzy Adamski, more

European Journal of Medicinal Chemistry > 2018 > 155 > C > 61-76

The human enzyme 17β-hydroxysteroid dehydrogenase 14 (17β-HSD14) oxidizes the hydroxyl group at position 17 of estradiol and 5-androstenediol using NAD⁺ as cofactor. However, the physiological role of the enzyme remains unclear. We recently described the first class of nonsteroidal inhibitors for this enzyme with compound 1 showing a high 17β-HSD14 inhibitory activity. Its crystal structure was used...

article

An Initial Study of a Lightweight Die Casting Die Using a Modular Design Approach

Sebastian Müller, Anke Müller, Felix Rothe, Klaus Dilger, more

International Journal of Metalcasting > 2018 > 12 > 4 > 870-883

High-pressure die casting dies are produced in most cases by conventional subtractive manufacturing processes. In this case, a massive design of the die usually ensures high stability during the casting process. However, at the same time, it leads to low flexibility in casting production and high material costs. The basic approach in the present work is to reduce the conventional subtractive production...

article

Outcome after early mobilization following hip reconstruction in children with developmental hip dysplasia and luxation

Katharina Susanne Gather, Eva Stillfried, Sebastien Hagmann, Sebastian Müller, more

World Journal of Pediatrics > 2018 > 14 > 2 > 176-183

Background Most orthopedic surgeons prefer spica cast immobilization in children for 4 to 12 weeks after surgical hip reconstruction in children with developmental hip dysplasia. This challenging treatment may be associated with complications. Studies are lacking that focus on early mobilization without casting for postoperative care after hip reconstruction. Methods Twenty-seven children (3.4±2...

article

Regularity of the Speed of Biased Random Walk in a One-Dimensional Percolation Model

Nina Gantert, Matthias Meiners, Sebastian Müller

Journal of Statistical Physics > 2018 > 170 > 6 > 1123-1160

We consider biased random walks on the infinite cluster of a conditional bond percolation model on the infinite ladder graph. Axelson-Fisk and Häggström established for this model a phase transition for the asymptotic linear speed $$\overline{\hbox {v}}$$ v¯ of the walk. Namely, there exists some critical value $$\lambda _{\hbox {c}}>0$$ λc>0 such that $$\overline{\hbox {v}}>0$$ v¯>0...

article

Point-by-point versus multisite electrode mapping in VT ablation: does freedom from VT recurrences depend on mapping catheter? An observational study

Petra Maagh, Arnd Christoph, Markus Sebastian Müller, Henning Dopp, more

Journal of Interventional Cardiac Electrophysiology > 2018 > 51 > 2 > 169-181

Purpose This study was conducted with the purpose of determining whether or not the potential technical advantages of multi-electrode mapping catheters in catheter ablation (CA) of ventricular tachycardia (VT) result in any relevant clinical benefit for VT patients. Methods A single-center VT study, having taken place from 2012 to 2014 using a standard 3.5-mm catheter (Thermocool SF® group 1) and...

article

Relevance of liver‐limited disease in metastatic colorectal cancer: Subgroup findings of the FIRE‐3/AIO KRK0306 trial

Julian Walter Holch, Ingrid Ricard, Sebastian Stintzing, Ludwig Fischer von Weikersthal, more

International Journal of Cancer > 142 > 5 > 1047 - 1055

In metastatic colorectal cancer (mCRC), liver‐limited disease (LLD) is associated with a higher chance of metastectomy leading to long‐term survival. However, limited data describes the prognostic and predictive relevance of initially unresectable LLD with regard to targeted first‐line therapy. The present analysis investigated the relevance of initially unresectable LLD in mCRC patients treated with...

article

Recalcitrant deep and shallow nodes in Aristolochia (Aristolochiaceae) illuminated using anchored hybrid enrichment

Stefan Wanke, Carolina Granados Mendoza, Sebastian Müller, Anna Paizanni Guillén, more

Molecular Phylogenetics and Evolution > 2017 > 117 > C > 111-123

Recalcitrant relationships are characterized by very short internodes that can be found among shallow and deep phylogenetic scales all over the tree of life. Adding large amounts of presumably informative sequences, while decreasing systematic error, has been suggested as a possible approach to increase phylogenetic resolution. The development of enrichment strategies, coupled with next generation...

Publication date

Last year (2)
Last 3 years (3)

Close

Date range setting

Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.

From:

To:
Set your own date range

Content availability

Available (137)
None (2)

Publication type

article (109)
book (30)

Publication language

English (130)
German (9)

Keywords

CAVITY RESONATORS (8)
INTEGRATED CIRCUIT MODELING (7)
PRINTED CIRCUIT BOARD (7)
IMPEDANCE (6)
CAPACITANCE (5)
NONHOMOGENEOUS MEDIA (4)
PAENIBACILLUS LARVAE (4)
POWER DISTRIBUTION NETWORK (4)
BIOMECHANICS (3)
COMPUTATIONAL MODELING (3)
CROSSTALK (3)
DELAYS (3)
EQUIVALENT CIRCUITS (3)
PARALLEL PLATES (3)
PHYSICS-BASED VIA MODEL (3)
PORTS (COMPUTERS) (3)
SCATTERING (3)
SCATTERING PARAMETERS (3)
SIGNAL AND POWER INTEGRITY (3)
TRANSMISSION LINE MATRIX METHODS (3)
ACCESS CONTROL (2)
ADVICE (2)
ANTIBACTERIAL AGENTS (2)
ANTIBAKTERIELLE AKTIVITÄT (2)
AUTOLOGOUS CHONDROCYTE IMPLANTATION (2)
C-C-KUPPLUNGEN (2)
CANCER STEM CELLS (2)
CARBONYLATION (2)
CARBONYLIERUNGEN (2)
CELL PAINTING (2)
CHEMOSELECTIVE OXIDATION (2)
COHESIVE ZONE (2)
COLLABORATION (2)
COMPANIES (2)
COMPUTATIONAL ELECTROMAGNETICS (2)
COUPLINGS (2)
C−C COUPLING (2)
ENERGY-AWARE ANALYSIS (2)
EQUIVALENT CIRCUIT MODEL (2)
FINITE-DIFFERENCE FREQUENCY-DOMAIN METHOD (2)
FRACTIONAL CALCULUS (2)
FREGE PROOFS (2)
GENE DUPLICATION (2)
GEOMETRY (2)
HALLSTATT CULTURE (2)
INVARIANCE PRINCIPLE (2)
LADDER GRAPH (2)
MATERIALS (2)
METHANOL-TO-HYDROCARBONS (2)
METHANOL-ZU-KOHLENWASSERSTOFFEN (2)
MULTI-TOUCH (2)
MUTUAL FUNDS (2)
NICHTRIBOSOMALE PEPTIDSYNTHESE (2)
NONLINEAR VISCOELASTICITY (2)
NONRIBOSOMAL PEPTIDE SYNTHESIS (2)
OLEFIN (2)
OLEFINE (2)
ORGANIC ELECTRONICS (2)
PACKAGE (2)
PERCOLATION (2)
POLYKETIDE SYNTHESIS (2)
POLYKETIDSYNTHESE (2)
POLYMER (2)
POWER SYSTEM RELIABILITY (2)
PRINTED CIRCUIT BOARD (PCB) (2)
PRINTED CIRCUITS (2)
PROOF COMPLEXITY (2)
PROTOTYPES (2)
RANDOM 3-SAT (2)
RANDOM WALK (2)
RATE OF ESCAPE (2)
REACTIVE OXYGEN SPECIES (ROS) (2)
REFLECTION (2)
REFUTATION ALGORITHMS (2)
SALINOMYCIN (2)
SIGNAL INTEGRITY (2)
SLOVAKIA (2)
STEREOSELECTIVE REDUCTIVE AMINATION (2)
STRIPLINE (2)
THRESHOLD LOGIC (2)
VIA MODEL (2)
VIAS (2)
VIRULENCE FACTORS (2)
VIRULENZFAKTOR (2)
VISCOPLASTICITY (2)
WAVEGUIDE LASERS (2)
ZEOLITES (2)
ZEOLITHE (2)
HERPETOSIPHON (1)
17Β-HYDROXYSTEROID DEHYDROGENASE TYPE 14 (1)
3+ OXIDATION STATE (1)
4-HYDROXYPHENYLGLYCINE (1)
ABCD-PARAMETERS (1)
ABLATION (1)
ACCESS CONTROL POLICIES (1)
ACCURACY (1)
ACOUSTIC EMISSION (1)
ACTIVATION ENERGY (1)
ACTIVE MANAGEMENT (1)
ACUTE MYELOID LEUKEMIA (1)
more

Data set

Elsevier (39)
Springer (35)
Wiley (32)
ieee (31)
CEJSH (2)

Journal

Angewandte Chemie (5)
Angewandte Chemie International Edition (5)
Gait & Posture (4)
Chemistry – A European Journal (3)
IEEE Electromagnetic Compatibility Magazine (3)
IEEE Transactions on Electromagnetic Compatibility (3)
Knee Surgery, Sports Traumatology, Arthroscopy (3)
Cell Reports (2)
Computer Science - Research and Development (2)
Environmental Microbiology (2)
Groundwater (2)
Journal of Statistical Physics (2)
Journal of Theoretical Probability (2)
Molecular Metabolism (2)
Molecular Phylogenetics and Evolution (2)
PAMM (2)
Procedia Materials Science (2)
Slovenská archeológia (Slovak Archaeology) (2)
physica status solidi (RRL) – Rapid Research Letters (2)
Acta Ophthalmologica (1)
Advanced Functional Materials (1)
Annals of Physics (1)
Annals of Pure and Applied Logic (1)
Archive for Mathematical Logic (1)
Archives of Microbiology (1)
Archives of Orthopaedic and Trauma Surgery (1)
Arthritis Research & Therapy (1)
BBA - Gene Regulatory Mechanisms (1)
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids (1)
Bioorganic & Medicinal Chemistry Letters (1)
Business and Society Review (1)
CIRP Annals - Manufacturing Technology (1)
Computational Materials Science (1)
Computational Mechanics (1)
Computer Methods in Applied Mechanics and Engineering (1)
Computers in Industry (1)
Current Applied Physics (1)
Cytometry Part A (1)
Decision Support Systems (1)
Discrete Mathematics (1)
Earth, Planets and Space (1)
Ethik in der Medizin (1)
European Financial Management (1)
European Journal of Medicinal Chemistry (1)
FEMS Yeast Research (1)
Helvetica Chimica Acta (1)
Hepatology (1)
IEEE Journal of Selected Topics in Quantum Electronics (1)
IEEE Transactions on Cognitive Communications and Networking (1)
IEEE Transactions on Components, Packaging and Manufacturing Technology (1)
Information and Computation (1)
International Journal of Cancer (1)
International Journal of Metalcasting (1)
International Journal of Production Economics (1)
International Journal of Research in Marketing (1)
International Journal on Software Tools for Technology Transfer (1)
Journal of Banking & Finance (1)
Journal of Banking and Finance (1)
Journal of Catalysis (1)
Journal of Financial Markets (1)
Journal of Foot and Ankle Research (1)
Journal of Interventional Cardiac Electrophysiology (1)
Journal of Materials Processing Technology (1)
Mathematische Zeitschrift (1)
Medizinrecht (1)
Molecular Plant (1)
NeuroImage (1)
Optical Materials (1)
Orthopädie & Rheuma (1)
Schmalenbach Business Review (1)
Software: Practice and Experience (1)
Sozial Extra (1)
Stochastic Processes and their Applications (1)
The Journal of Allergy and Clinical Immunology (1)
The Lancet Oncology (1)
Transfusion (1)
World Journal of Pediatrics (1)
Zeitschrift für öffentliches Recht (1)
more

INFONA - science communication portal

Search results for: Sebastian Müller

A 19‐color single‐tube full spectrum flow cytometry assay for the detection of measurable residual disease in acute myeloid leukemia

Grammar‐based fuzzing of data integration parsers in computational materials science

How to Find Aquifer Statistics Utilizing Pumping Tests? Two Field Studies Using welltestpy

Do consumers care about work health issues? A qualitative study on voluntary occupational health activities and consumer social responsibility

ogs5py: A Python‐API for the OpenGeoSys 5 Scientific Modeling Package

Cover Feature: Salinomycin Derivatives Kill Breast Cancer Stem Cells by Lysosomal Iron Targeting (Chem. Eur. J. 33/2020)

Salinomycin Derivatives Kill Breast Cancer Stem Cells by Lysosomal Iron Targeting

DMT1 Inhibitors Kill Cancer Stem Cells by Blocking Lysosomal Iron Translocation

Image‐Based Morphological Profiling Identifies a Lysosomotropic, Iron‐Sequestering Autophagy Inhibitor

Image‐Based Morphological Profiling Identifies a Lysosomotropic, Iron‐Sequestering Autophagy Inhibitor

The new LassoLoop360° technique for biomechanically superior tissue grip

Einstein Relation for Random Walk in a One-Dimensional Percolation Model

Dielectric–Semiconductor Interface Limits Charge Carrier Motion at Elevated Temperatures and Large Carrier Densities in a High‐Mobility Organic Semiconductor

Structure-based design and profiling of novel 17β-HSD14 inhibitors

An Initial Study of a Lightweight Die Casting Die Using a Modular Design Approach

Outcome after early mobilization following hip reconstruction in children with developmental hip dysplasia and luxation

Regularity of the Speed of Biased Random Walk in a One-Dimensional Percolation Model

Point-by-point versus multisite electrode mapping in VT ablation: does freedom from VT recurrences depend on mapping catheter? An observational study

Relevance of liver‐limited disease in metastatic colorectal cancer: Subgroup findings of the FIRE‐3/AIO KRK0306 trial

Recalcitrant deep and shallow nodes in Aristolochia (Aristolochiaceae) illuminated using anchored hybrid enrichment

Filter options

Publication date

Content availability

Publication type

Publication language

Keywords

Data set

Journal

INFONA - science communication portal

Search results for: Sebastian Müller

Add recipient

Sending message cancelled

Are you sure you want to cancel sending this message?

Send message

Filter options

Publication date

Date range setting

Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.

Content availability

Publication type

Publication language

Keywords

Data set

Journal

Reporting an error / abuse

Sending the report failed

Accessibility options