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Die Protonentherapie ist eine Form der Teletherapie in der Radioonkologie, welche verwendet wird, um maligne Tumoren zu behandeln. Die Protonen werden im Zyklotron oder Synchrotron beschleunigt, um die Tumoren mit hochenergetischen Partikeln von bis zu 230 Megaelektronenvolt (MeV) mittels Passive-Scattering- oder aktivem Scanning-Beam-Verfahren zu bestrahlen. Durch die spezifischen physikalischen...
Purpose: To investigate the effect of the dual EGFR/HER2 (ErbB2) tyrosine kinase inhibitors BIBW 2992 and BIBW 2669 on proliferation and clonogenic cell survival of FaDu human squamous cell carcinoma in vitro, and on tumor growth after single-dose irradiation in nude mice. Material and Methods: Cell proliferation, cell-cycle distribution and clonogenic cell survival after irradiation were assayed...
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