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We compared changes in nocturia and sleep related parameters between the anticholinergic solifenacin and placebo in patients with overactive bladder associated with nocturia. We performed subgroup analysis of data from a randomized, controlled trial of solifenacin (5 or 10 mg) in Japan. Men and women 20 years old or older with overactive bladder were eligible for study participation. Patients who...
Objectives To examine the mechanism underlying improvements in nocturia by α1-blockers, we investigated whether the α1-blocker naftopidil acts on nocturia with sleep disturbance using a frequency/volume chart (FVC). Methods A total of 56 male patients with lower urinary tract symptoms were enrolled. The inclusion criteria were as follows: eight or more points on the I-PSS; three or more points on...
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