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Hemoglobins are ubiquitous in nature and among the best-characterized proteins [1–9]. Genetics has revealed crucial roles for human hemoglobins [10], but similar data are lacking for plants. Plants contain symbiotic and nonsymbiotic hemoglobins [11]; the former are thought to be important for symbiotic nitrogen fixation (SNF). In legumes, SNF occurs in specialized organs, called nodules, which contain...
Mutations in the gene encoding the gap junction protein connexin26 (Cx26) are responsible for the autosomal recessive isolated deafness, DFNB1, which accounts for half of the cases of prelingual profound hereditary deafness in Caucasian populations [1–5]. To date, in vivo approaches to decipher the role of Cx26 in the inner ear have been hampered by the embryonic lethality of the Cx26 knockout mice...
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