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Objective To study and evaluate the effect of Sangu Decoction (SGD, 三骨汤) on the bone destruction due to mammary cancer metastasis. Methods Metastasis rat mammary tumor-1 cells were transplanted into the left hind limb tibia of SD rats to establish the bone metastasis of the mammary cancer model. The modeled rats were treated with SGD for observing its effect on rats’ pain behavior, including 50%...
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