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Fmoc/tBu-protected peptides, synthesized on 2-chlorotrityl resin (CLTR), have been quantitatively esterified by treatment with 2-chlorotrityl chloride (Clt-chloride) and diisopropylethylamine (DIPEA). The obtained peptide Clt-esters have been deprotected at the N α -function and subsequently condensed in solution to larger peptides. The Clt-function of the obtained products could be selectively...
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