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Alternative splicing is associated with human disease. In acute promyelocytic leukaemia (APL) patients with the long (L)‐type promyelocytic leukaemia‐retinoic acid receptor α fusion gene (PML‐RARA), three alternative splicing isoforms can be detected: E5(+)E6(+), E5(−)E6(+), and E5(−)E6(−). This study is the first to demonstrate that alternative splicing of L‐type PML‐RARA is associated with time...
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