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VR environment and task‐dependent cross‐hemispheric functional shift in the hippocampus. Top: Side view of the east building and examples of objects used the current study. Middle: Sagittal (right) and coronal (left) section showing the peak activity in the left hippocampus during the object‐cueing period. Bottom: Sagittal (right) and coronal (left) section showing the peak activity in the right hippocampus...
The hippocampus plays critical roles in both object‐based event memory and spatial navigation, but it is largely unknown whether the left and right hippocampi play functionally equivalent roles in these cognitive domains. To examine the hemispheric symmetry of human hippocampal functions, we used an fMRI scanner to measure BOLD activity while subjects performed tasks requiring both object‐based event...
The medial entorhinal cortex layer II (MEClayerII) is a brain region critical for spatial navigation and memory, and it also demonstrates a number of changes in patients with, and animal models of, temporal lobe epilepsy (TLE). Prior studies of GABAergic microcircuitry in MEClayerII revealed that cholecystokinin‐containing basket cells (CCKBCs) select their targets on the basis of the long‐range projection...
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