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25‐Hydroxyvitamin D3 (25(OH)D3) is a prohormone and a major vitamin D metabolite. The discovery of (25(OH)D3) 1α‐hydroxylase in many vitamin D target organs has yielded an increased interest in defining the role(s) of 25(OH)D3 in these tissues. The etiology of cancer appears to be complex and multi‐factorial. Cellular stress (e.g., DNA damage, hypoxia, oncogene activation) has been identified as one...
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