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BackgroundThis study elucidated the association between histopathological factors and the prognosis of oral carcinoma. As the histopathological factors were determined from the surgical specimen and this can only be used for the choices of postoperative regimens, this study also investigated the linkage between prognostic factors and the expression of key molecules to examine the feasibility of markers...
BackgroundMicroRNAs play important roles in carcinogenesis. A preliminary screening study suggested that down‐regulation of miR‐370 occurs in oral squamous cell carcinoma (OSCC) tissue. Insulin receptor substratre‐1 (IRS‐1) is the substrate of insulin‐like growth factor receptor (IGFR), which modulates AKT/mTOR activation in malignancies. The relationship between miR‐370 and IRS‐1, and their functional...
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