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Objectves
Transient receptor potential vanilloid 3 (TRPV3) is a member of the TRP channels family of Ca2+‐permeant cation channels. In this study, we aim to investigate the role of TRPV3 in pulmonary vascular remodeling and PASMCs proliferation under hypoxia.
Materials and methods
The expression of TRPV3 was evaluated in patients with pulmonary arterial hypertension (PAH) and hypoxic rats, using...
ObjectivesPulmonary arterial hypertension (PAH) is a fast progressing vascular disease characterized by uncontrolled cell proliferation of pulmonary artery smooth muscle cells (PASMCs). Some studies have suggested that PAH and cancers share an apoptosis‐resistant state, featuring excessive cell proliferation. The miR‐34 family consists of tumour‐suppressive miRNAs, and its reduced expression has been...
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