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Tracer kinetic model selection for dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) data analysis influences its use as a prognostic biomarker. Our aim was to find DCE-MRI parameters that predict 1-year survival (1YS) and overall survival (OS) among patients with advanced hepatocellular carcinoma (HCC) treated with antiangiogenic monotherapy by conducting a proof-of-concept comparative...
This study was designed to characterize the spatio-temporal properties of intratumoral enhancement patterns by using voxel-wise temporal enhancement spectra and morphometry of their spatial distributions in dynamic contrast-enhanced (DCE) breast MRI. Discrete Fourier transformation (DFT) and singular value decomposition (SVD) were used to extract the temporal enhancement features for comparison, generating...
This study is designed to segment suspicious regions using automatic computerized procedures and to classify kinetic patterns using commercially available three-time-points (3TP) method of computer- aided diagnosis. A novel evaluation method using perfusion volume fractions is introduced for examining meaningful kinetic features in differentiation of benign and malignant breast lesions. Dynamic contrast-...
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