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The LMNA gene, which encodes the nuclear envelope protein lamin A/C, is considered to be the most common autosomal disease gene associated with familial dilated cardiomyopathy. To date, each mutation of the LMNA gene has been associated with a specific disease phenotype. Clinical data, family histories, and blood samples were collected from 27 biological members of a family with dilated cardiomyopathy,...
The bioeffects of EMP exposure on mice lymphocytes are observed. Mice were whole-body exposed to different field intensity of EMP (0, 50, 100, 200 and 400 kV/m) for 200 pulses. The effects of EMP exposure on mice lymphocytes proliferation were studied by 3H-thymidine ( 3H-TdR) incorporation. Cell cycle was evaluated by flow cytometry (FCM). The ultrastructure of mice lymphocytes was observed by transmission...
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