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Signal transducer and activator of transcription 5 (STAT5) is activated in CD34+/CD38− acute myelogenous leukemia (AML) cells. Inhibition of STAT5 induced apoptosis and sensitized these cells to the growth inhibition mediated by conventional chemotherapeutic agents. The present study attempted to identify molecules that are regulated by STAT5 in CD34+/CD38− AML cells by utilizing cDNA microarrays,...
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