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Objectives
Skin barrier disruption is a significant problem of the older population in an aging society. It is characterized by increased transepidermal water loss and decreased skin water content, and particulate matter (PM) is a social issue that can contribute to the exacerbation of skin inflammation. Thus, addressing this problem is urgent.
Methods
Skin barrier‐disrupted mouse models were induced...
Background
Hyaluronic acid (HA) is mainly used to treat xerosis. It also exerts wound‐healing, moisturizing, and antiaging effects. Although HA is considered an effective and safe ingredient in cosmetics, there is a constant demand for a more money‐saving and effective formulation. This study aimed to evaluate the safety and efficacy of a novel hydrogel‐based moisturizer containing HA cross‐linked...