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Nanocomposites hydrogel (nanohydrogel) composed of chitosan (CS) and montmorillonite (MMT) were prepared and systematically studied for drug release behavior following electrostimulation. The deterioration of the responsiveness and reversibility of CS upon repeated on–off electrostimulation switching operations are major limitations for clinical applications, as it suffers from too much structural...
Electrostimulus-responsive hybrid composites composed of chitosan (CS) and clay were successfully developed and systematically characterized. The addition of negatively charged clay as an ionic cross-linker strongly affect the cross-linking density as well as the mechanical property, swelling–deswelling behavior and fatigue property of the hybrids. With lower clay content, the crystallinity of the...
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