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Vanadate and chromate reduction in the presence of biocomponents like saccharides and L-ascorbic acid is demonstrated to generate V(IV) and Cr(III) species, respectively. The incipiently formed V(IV) and Cr(III) species are demonstrated to cause single strand and plasmid DNA nicking, lipid peroxidation and cytotoxicity in isolated rat hepatocytes. The V(IV) complexes depleted the levels of non-enzymatic...
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