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Clinopodium chinense (Benth.) O. Ktze (Labiatae), known as ‘Duanxueliu’ in the Chinese Pharmacopoeia, has been widely used as a traditional Chinese medicine for the treatment of hemorrhagic disease. Total flavonoids from Clinopodium chinense (Benth.) O. Ktze (TFCC), the most active ingredient, possess a variety of properties, such as antioxygenation. Until now, evidence-based toxicity data on TFCC...
Previous reports reveal that Isoliquiritigen(ISL), a licorice flavonoid, possesses various antitumour properties, cyclophosphamide, an alkylating agent, has various genotoxic and carcinogenic effects, and to be involved in some secondary neoplasmas. However, it is still used extensively as an antitumour agent and immunosuppressant in the clinic. In order to find out whether isoliquiritigen could enhance...
Heroin addiction caused oxidative stress was testified for the first time in mice. After administered with heroin, mice not only showed decreased total antioxidant capacity as well as antioxidant enzymes such as, SOD, CAT and GPx in brain, but also include oxidative damage of DNA, protein and lipid. On the other hand, exogenous antioxidants could restrain the oxidative stress, even alleviate withdrawal...
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