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Tetracycline Three Times Daily Versus Four Times Daily in Bismuth‐Containing Quadruple Therapy as the First‐Line Treatment of Helicobacter pylori Infection: A Multicenter, Noninferiority, Randomized Controlled Trial

Yu‐Ming Ding, Qiu‐Mei Zhang, Rui‐Li Li, Zhong‐Xue Han, więcej

Background Current guidelines recommend bismuth‐containing quadruple therapy for patients newly diagnosed with Helicobacter pylori (H. pylori) infection. We aimed to compare the efficacy and safety of tetracycline administered three times daily versus four times daily in bismuth‐containing quadruple therapy for first‐line treatment of H. pylori infection. Methods This multicenter, noninferiority,...

artykuł

The effect of VEGF stimulation in diabetic foot ulcers: A systematic review

Frederik S. Bang, Veronica Leeberg, Ming Ding, Chris H. Dreyer

Wound Repair and Regeneration > 32 > 4 > 384 - 392

Diabetic foot ulcers are a common and severe complication of diabetes mellitus, and a risk factor for amputation. Because of the vessel insufficiency in diabetic foot ulcers (DFU), vascular endothelial growth factor (VEGF) that simulates angiogenesis is of interest to promote wound healing. This systematic review evaluates the last 16 years of in‐vivo studies with VEGF stimulation as a treatment for...

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Efficacy and safety of a 14‐day modified concomitant therapy for refractory Helicobacter pylori infection: a pilot study

Shu‐yan Zeng, Juan Wang, Jing Liu, Min‐Juan Lin, więcej

Journal of Gastroenterology and Hepatology > 38 > 12 > 2097 - 2103

Background and Aim After three treatment failures, Helicobacter pylori infection is deemed refractory as antibiotic treatment options become significantly limited. This study evaluated the efficacy and safety of a 14‐day modified concomitant therapy for managing refractory H. pylori infection. Methods Patients who had failed to respond to three or more rounds of H. pylori therapies were recruited...

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Curcumin alleviates bisphenol AF‐induced oxidative stress and apoptosis in caprine endometrial epithelial cells via the Nrf2 signaling pathway

Ming Liu, Xu Zhou, Xiao‐Jie Wang, Yong‐Sheng Wang, więcej

Environmental Toxicology > 38 > 12 > 2904 - 2914

Bisphenol AF (BPAF), a BPA‐substitute, has been widely used in industrial compounds throughout the world. Several studies have shown that BPAF has endocrine interference and reproductive toxicity. However, the toxic effects of BPAF on pregnancy and placenta of goats are still unclear. Therefore, the objective of this study was to reveal the toxic effect of BPAF by using an in vitro culture model of...

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A shift of vector specificity acquired by a begomovirus through natural homologous recombination

Yun‐Yun Fan, Yu‐Wei Zhong, Li‐Long Pan, Xiao‐Wei Wang, więcej

Molecular Plant Pathology > 24 > 8 > 882 - 895

Recombination is common in plant viruses such as geminiviruses, but the ecological and pathogenic consequences have been explored only in a few cases. Here, we found that a new begomovirus, tomato yellow leaf curl Shuangbai virus (TYLCSbV), probably originated from the recombination of Ageratum yellow vein China virus (AYVCNV) and tobacco curl shoot virus (TbCSV). Agrobacterium‐mediated inoculation...

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Effect of maleylation and denaturation of human serum albumin on its interaction with scavenger receptors

Xiao‐Lei Li, Zeng‐Shuai Yan, Yu‐Qiang Ma, Hong‐Ming Ding

Proteins: Structure, Function, and Bioinformatics > 91 > 8 > 1140 - 1151

The specific recognition of serum proteins by scavenger receptors is critical and fundamental in many biological processes. However, the underlying mechanism of scavenger receptor‐serum protein interaction remains elusive. In this work, taking scavenger receptors class A1 (SR‐A1) as an example, we systematically investigate its interaction with human serum albumin (HSA) at different states through...

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High‐dose synthetic phenolic antioxidant propyl gallate impairs mouse oocyte meiotic maturation through inducing mitochondrial dysfunction and DNA damage

Sheng‐Ji Yang, Yong‐Sheng Wang, Li‐Dan Zhang, Zhi‐Ming Ding, więcej

Environmental Toxicology > 38 > 8 > 1800 - 1810

Propyl gallate (PG) is one of the most widely used antioxidants in food products, cosmetics and pharmaceutical industries. Increased research has suggested that exposure to PG influences reproductive health in humans and animals. However, until now, it has not yet been confirmed whether PG would impact oocyte quality. In this study, the hazardous effects of PG on oocyte meiotic maturation were investigated...

artykuł

Disrupted Topological Organization of White Matter Network in Angelman Syndrome

Lei Wei, Xiaonan Du, Zidong Yang, Ming Ding, więcej

Journal of Magnetic Resonance Imaging > 57 > 4 > 1212 - 1221

Background Angelman syndrome (AS) is a genetic disorder that affects neurodevelopment. The investigation of changes in the brain white matter network, which would contribute to a better understanding of the pathogenesis of AS brain, was lacking. Purpose To investigate both local and global alterations of white matter in patients with AS. Study Type Prospective. Subjects A total of 29 AS patients...

artykuł

Risk factors that predict major amputations and amputation time intervals for hospitalised diabetic patients with foot complications

Yu‐Yu Chou, Chin‐Chun Hou, Chien‐Wei Wu, Dun‐Wei Huang, więcej

International Wound Journal > 19 > 6 > 1329 - 1338

Diabetes‐related lower extremity amputations are an enormous burden on global health care and social resources because of the rapid worldwide growth of the diabetic population. This research aimed to determine risk factors that predict major amputation and analyse the time interval from first hospitalisation to amputation by using standard management protocols and Kaplan–Meier survival curves. Data...

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Clinical practice of Helicobacter pylori infection management by gastroenterologists in secondary and tertiary hospitals: A stratified sampling cross‐sectional survey

Wen Lin Zhang, Yue Yue Li, Jing Liu, Juan Wang, więcej

Journal of Digestive Diseases > 23 > 7 > 365 - 375

Objective To investigate the management of Helicobacter pylori (H. pylori) infection by gastroenterologists from secondary and tertiary hospitals in Shandong Province, China, where there is a high prevalence of H. pylori infection. Methods A questionnaire‐based, stratified sampling survey was conducted from June 1 to August 30, 2021. The ratio of secondary to tertiary hospitals was set at 2:1....

artykuł

ERF4 interacts with and antagonizes TCP15 in regulating endoreduplication and cell growth in Arabidopsis

An‐Ming Ding, Chuan‐Tao Xu, Qiang Xie, Ming‐Jin Zhang, więcej

Journal of Integrative Plant Biology > 64 > 9 > 1673 - 1689

Endoreduplication is prevalent during plant growth and development, and is often correlated with large cell and organ size. Despite its prevalence, the transcriptional regulatory mechanisms underlying the transition from mitotic cell division to endoreduplication remain elusive. Here, we characterize ETHYLENE‐RESPONSIVE ELEMENT BINDING FACTOR 4 (ERF4) as a positive regulator of endoreduplication through...

artykuł

Implementation of WeChat‐based patient–doctor interaction in the management of Helicobacter pylori infection: A propensity score matching analysis

Bo Shen Lin, Yue Yue Li, Chen Qiao, Jing Liu, więcej

Journal of Digestive Diseases > 23 > 5-6 > 280 - 287

Objective We aimed to investigate if the WeChat‐based patient–doctor interaction could affect treatment outcomes of Helicobacter pylori (H. pylori) eradication compared with conventional patient education (CPE) alone. Methods Patients treated for H. pylori infection for the first time at our clinic from 1 July 2019 to 31 July 2021 were retrospectively included and divided into the CPE and WeChat...

artykuł

Professional identity and emotional labour affect the relationship between perceived organisational justice and job performance among Chinese hospital nurses

Jing‐Fen Yu, Yue‐Ming Ding, Rui‐Ying Jia, Dan‐Dan Liang, więcej

Journal of Nursing Management > 30 > 5 > 1252 - 1262

Aim To investigate the influence of perceived organisational justice, professional identity and emotional labour on nurses' job performance. Background Previous studies have not explored the impact of professional identity and emotional labour on the relationship between perceived organisational justice and job performance. However, how to mobilize the enthusiasm of nurses and improve their job...

artykuł

Efficacy of bioreactor‐activated bone substitute with bone marrow nuclear cells on fusion rate and fusion mass microarchitecture in sheep

Ming Ding, Kariatta Esther Koroma, David Wendt, Ivan Martin, więcej

Journal of Biomedical Materials Research Part B: Applied Biomaterials > 110 > 8 > 1862 - 1875

Bioreactors have been used for bone graft engineering in pre‐clinical investigations over the past 15 years. The ability of bioreactor‐incubated bone marrow nuclear cells (BMNCs) to enhance bone‐forming potential varies significantly, and the three‐dimensional (3D) distribution of BMNCs within the scaffold is largely unknown. The aims of this study were (1) to investigate the efficacy of a carbonated...

artykuł

Bisphenol F exposure affects mouse oocyte in vitro maturation through inducing oxidative stress and DNA damage

Zhi‐Ming Ding, Yang‐Wu Chen, Muhammad Jamil Ahmad, Yong‐Sheng Wang, więcej

Environmental Toxicology > 37 > 6 > 1413 - 1422

Bisphenol F (BPF), a substitute for bisphenol A (BPA), is progressively used to manufacture various consumer products. Despite the established reproductive toxicity of BPF, the underlying mechanisms remain to elucidate. This in‐vitro study deep in sighted the BPF toxicity on mouse oocyte meiotic maturation and quality. After treating oocytes with BPF (300 μM), the oocyte meiotic progression was blocked,...

artykuł

A γ‐glutamyl hydrolase lacking the signal peptide confers susceptibility to folates/antifolates in acute lymphoblastic leukemia cells

Shuxuan Wang, Yao Chen, Houshun Fang, Yan Xu, więcej

FEBS Letters > 596 > 4 > 437 - 448

A key cofactor of several enzymes implicated in DNA synthesis, repair, and methylation, folate has been shown to be required for normal cell growth and replication and is the basis for cancer chemotherapy using antifolates. γ‐Glutamyl hydrolase (GGH) catalyzes the removal of γ‐polyglutamate tails of folylpoly‐/antifolylpoly‐γ‐glutamates to facilitate their export out of the cell, thereby maintaining...

artykuł

Recent Advances in Complex Hollow Electrocatalysts for Water Splitting

Yi Zhong Wang, Min Yang, Yi‐Ming Ding, Nian‐Wu Li, więcej

Advanced Functional Materials > 32 > 6 > n/a - n/a

Electrochemical water splitting powered by renewable energy sources has been considered as an attractive hydrogen generation technology with high‐purity product and zero carbon emission. However, the efficient realization of large‐scale water splitting is severely hampered by the sluggish hydrogen/oxygen evolution reaction (HER/OER). As an important class of functional materials, complex hollow electrocatalysts...

artykuł

RNF168 suppresses the cancer stem cell‐like traits of nonsmall cell lung cancer cells by mediating RhoC ubiquitination

Guoxiang Rong, Zhongjun Pan, Ming Ding, Lihui Wang

Environmental Toxicology > 37 > 3 > 603 - 611

The critical roles of E3 ubiquitin ligase RNF168 have been widely revealed in various tumors, however, its roles in lung cancer progression are still confusing. Here, we found that RNF168 expression is positively correlated with the overall survival, first‐progression survival, and postprogression survival of lung adenocarcinoma, but not correlated with these survivals of squamous cell carcinoma of...

artykuł

Private‐encoder: Enforcing privacy in latent space for human face images

Yuan Zhao, Bo Liu, Tianqing Zhu, Ming Ding, więcej

Concurrency and Computation: Practice and Experience > 34 > 3 > n/a - n/a

The explosive growth of various computer vision technologies generates a tremendous amount of visual data online every day. In addition to bringing convenience and revolutionizing our daily life, image data also reveal a wide range of sensitive information and pose unprecedented privacy leakage risks. Particularly, in the case of photos contain human faces, people can easily access those face images...

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Benzophenone‐3 breaches mouse Sertoli cell barrier and alters F‐actin organization without evoking apoptosis

Xi‐Yu Zhang, Xiao‐Fei Jiao, Di Wu, Fan Chen, więcej

Environmental Toxicology > 37 > 1 > 28 - 40

Benzophenone‐3 (BP‐3), one of the most commonly utilized ultraviolet filters in personal care products, has aroused public concern in recent years for its high chances of human exposure. Previous studies have found that BP‐3 can impair testes development and spermatogenesis, but the targets of BP‐3 are still unknown. In this study, primary Sertoli cells from 20‐day‐old mice were treated in vitro with...

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