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Improving the accuracy and efficiency of computational RNA secondary structure prediction is an important challenge, particularly for pseudoknotted secondary structures. We propose a new approach for prediction of pseudoknotted structures, motivated by the hypothesis that RNA structures fold hierarchically, with pseudoknot free pairs forming initially, and pseudoknots forming later so as to minimize...
RNA molecules are crucial in different levels of cellular function, ranging from translation and regulating genes to coding for proteins. Additionally, nucleic acids (RNA and DNA molecules) are designed for novel applications in biotechnology. Understanding the structure of a molecule is important in inferring its function, and computational methods for structure prediction have captured the interest...
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