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In current biological image analysis, the temporal stage information, such as the developmental stage in the Drosophila development in situ hybridization images, is important for biological knowledge discovery. Such information is usually gained through visual inspection by experts. However, as the high-throughput imaging technology becomes increasingly popular, the demand for labor effort on annotating,...
In current developmental research, one of the challenging tasks is to understand the spatio-temporal gene expression patterns and the relationships among different genes. In situ hybridization (ISH) assay which shows mRNA spatio-temporal expression patterns in cells and tissues directly is currently widely utilized in the bench work. With the increasing of available ISH images, automatic annotation...
The fast development of microscopy imaging techniques nowadays promotes the generation of a large amount of data. These data are very crucial not only for theoretical biomedical research but also for clinical usage. In order to decrease the inter-intra observer variability and save the human effort on labeling and classifying these images, a lot of research efforts have been devoted to the development...
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