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Limited data exist with respect to the outcome and optimal treatment of patients with myelomatous involvement of the central nervous system (CNS).Of 4060 patients with multiple myeloma (MM), evaluated at Mayo Clinic from 1998 to 2014, 29 (0.7%) had identifiable CNS involvement, established by the presence of atypical plasma cells in the cerebrospinal fluid (CSF) and/or identification of intraparenchymal...
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