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L-type calcium current (I Ca-L ) alterations are implicated in various cardiac diseases, and the lysophosphatidic acid (LPA) level increases in several ischemic heart diseases. We investigated the effects of LPA on I Ca-L in normal and H 2 O 2 -treated neonatal rat ventricular myocytes. LPA treatment (24h) increased the action potential duration (APD) and I Ca-L...
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