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Translation of mitochondrial encoded mRNAs occurs on mitochondrial ribosomes. The ribosomal RNA components of the mitochondrial ribosomes are coded for by mitochondrial DNA, while all the protein subunits are coded for by nuclear chromosomes. The only mitochondrial protein subunit cloned in mammals is MRPL12, making the study of the role of mitochondrial translation in human disease difficult. We...
There are four known members of the C/EBP family of basic region-leucine zipper transcription factors: Cebpa, Cebpb, Cebpd, and Cebpe. Cebpa has previously been mapped to mouse chromosome 7. Here, we show that Cebpb maps to mouse chromosome 2, Cebpd to chromosome 16, and Cebpe to chromosome 14. The assignment of Cebpd to chromosome 16 identifies a new region of homology between mouse chromosome 16...
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