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A selenium-modified hyaluronic acid (HA) compound (SeHA) was synthesized as a mimic of glutathione peroxidase (GPX). IR and NMR spectra of SeHA predict that the —CH 2 OH group of the N-acetyl-D-glucosamine in HA was modified by group —SeH. There are averagely 152 —SeH groups in one SeHA molecule. The GPX activities are 103. 88, 32. 15 and 152. 71 U/μmol, respectively, when the substrates were...
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